Alzheimer’s disease (AD) is a common form of dementia. It’s characterized by the presence of amyloid beta and Tau protein plaques. Unfortunately, there’s no permanent cure for AD. The FDA has approved drugs like cholinesterase inhibitors, NMDA receptor antagonists, and immunotherapies, but they only provide temporary relief and can’t repair damaged neurons in AD.
Researchers worldwide are working hard to find new treatment approaches and innovative therapies. Among these, stem cell therapy shows promise. Stem cells have the unique ability to differentiate into different cell types, making them a potential treatment for AD. Pre-clinical studies have shown positive results.
Mesenchymal stem cells, in particular, are undergoing various phases of clinical trials. Although they hold promise, further advancements are needed to make this therapy widely available.
Over the past decade, research has generated multiple hypotheses about the pathology of AD. There have been significant developments in therapeutic strategies, including immunotherapy and stem cell therapy. These treatments are currently in clinical trials, offering hope to individuals affected by AD.
While a definitive cure for AD is still elusive, ongoing research and innovative treatments are bringing hope for the future.
Khan T, Waseem R, Shahid M, Ansari J, Ahanger IA, Hassan I, Islam A. Recent Advancement in Therapeutic Strategies for Alzheimer’s Disease: Insights from Clinical Trials. Ageing Res Rev. 2023 Oct 31:102113. doi: 10.1016/j.arr.2023.102113. Epub ahead of print. PMID: 37918760.